Microbial Invasion During Parenteral Nutrition in Surgical Infants Receiving Glutamine

Institute of Child Health60 enrolled

Overview

We hypothesise that the addition of glutamine supplementation to both parenteral nutrition and enteral feeds in surgical newborn infants leads to a reduction in bacterial invasion.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

TRIPLE

Enrollment

Conditions

Surgical Infants Requiring Total Parenteral Nutrition

Interventions

Isonitrogenous VaminolactDIETARY_SUPPLEMENT

Isonitrogenous Vaminolact

Dipeptiven (L-glutamine- Lalanine)DRUG

0.6g/kg/day

Eligibility

Sex: ALLMax age: 3 Months

Medical Language ↔ Plain English

Inclusion Criteria: * Infants who have undergone surgical procedures for congenital anomalies or * Intestinal inflammation who require total parenteral nutrition. Exclusion Criteria: \-

Locations (1)

Institute of Child Health, 30 Guilford Street

London, United Kingdom

Outcomes

Primary Outcomes

Evidence of microbial invasion

Time frame: 5 days

Data from ClinicalTrials.gov

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