Hsp90 is a chemical in the body that is involved in promotion of cancer. SNX-5422 is an experimental drug that blocks Hsp90. It is being evaluated for safety and efficacy in patients with cancer.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
32
dose escalated, tablets twice a week; undetermined duration until disease progression
Pfizer Investigational Site
Bethesda, Maryland, United States
MTD, safety and toxicity
Time frame: continuous
pharmacokinetic profile of SNX-5422
Time frame: first cycle
tumor response measured by X-rays or scans
Time frame: after every 2 cycles
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