The objectives of this study were to study the pharmacokinetics, pharmacodynamics and safety of Org 36286 after a single subcutaneous administration in healthy females.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
24
Maximum number of follicles >= 5 mm (nmax)
Time frame: Days 2 - 35
Mean dose-normalized maximum plasma concentration (Cmax) post single dose Org 36286
Time frame: Days 1 - 15
Mean dose-normalized area under the curve (AUC) post single dose Org 36286
Time frame: Days 1 - 15
Mean total plasma clearance (CL) post single dose Org 36286
Time frame: Days 1 - 15
Number of participants with an adverse event (AE)
Time frame: Start of treatment up to day 28
Day on which the number of follicles >= 5 mm was equal to nmax for the first time (dmax)
Time frame: Days 2 - 35
Total number of follicles >= 5 mm per day
Time frame: Days 2 - 35
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