The primary objectives were to determine the efficacy and safety of the GITS formulation of Doxazosin in Taiwanese patients with prostate enlargement.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
80
Subjects initiated on 4 mg doxazosin GITS once daily at Visit 1 for four weeks. At Visit 2 (Week 4) increased to 8 mg Doxazosin GITS if efficacy response criteria not met.
Pfizer Investigational Site
Kaohsiung City, Taiwan
Pfizer Investigational Site
Taichung, Taiwan
Pfizer Investigational Site
Taipei, Taiwan
Pfizer Investigational Site
Taoyuan District, Taiwan
Change in the maximum urinary flow rate (Qmax) from baseline
Time frame: 8 weeks
Change in the International Prostate Symptom Score (IPSS) total score from baseline
Time frame: 8 weeks
Change in the International Prostate Symptom Score (IPSS) total score from baseline
Time frame: 4 weeks
Change in the maximum urinary flow rate (Qmax) from baseline
Time frame: 4 weeks
Change in the quality of life (QoL) assessment index score from baseline
Time frame: 8 weeks
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