A Study of ARQ 197 in Healthy Volunteers to Assess the Pharmacokinetic (PK) Profile in Extensive and Poor Metabolizers as Defined by Cytochrome P450 2C19 (CYP 2C19) Genotype

Inclusion Criteria: * Subject must provide written informed consent prior to any study related procedures * Subjects must be between the ages of 18 and 65 years old * Male participants must be surgically sterilized * Female participants must be surgically sterilized or post menopausal and must have a negative serum pregnancy test. Post Menopausal is defined as at least one year without menses. * Subject must, in the opinion of the Investigator, be willing and able to complete the study procedures Exclusion Criteria: * Subject must provide written informed consent prior to any study related procedures * Subjects must be between the ages of 18 and 65 years old * Male participants must be surgically sterilized * Female participants must be surgically sterilized or post menopausal and must have a negative serum pregnancy test. Post Menopausal is defined as at least one year without menses. * Subject must, in the opinion of the Investigator, be willing and able to complete the study procedures