Effect of an Allergen Vaccine in Patients With Allergic Rhino-Conjunctivitis and Asthma Due to House Dust Mite Allergy

Inclusion Criteria: * Mild to moderate perennial allergic rhinoconjunctivitis due to sensitization against house dust mites * Mild asthma * Females only if non-reproductive or agree to practice an effective and accepted method of contraception Exclusion Criteria: * Relevant cardiovascular, renal, pulmonary or endocrine disease * History of autoimmune disease * Severe allergies * History of active infectious disease * Current diagnosis or history of malignancy * Relevant neurological or psychiatric disorder * Pregnancy or lactation * History of alcohol abuse or other recreational drugs * Use of an investigational drug within three month before enrolment * Blood donation within 30 days before enrolment