Racial Differences: Nitric Oxide(NO) and Endothelin-1(ET-1) in Preeclampsia (PreE)

University of Mississippi Medical Center52 enrolled

Overview

The goal of this study is to examine the activation of markers of endothelial and cardiovascular dysfunctions, from women with high-risk pregnancies. Information from this study will hopefully provide enough information to determine a link between race, the advent of high risk pregnancies and cardiovascular markers. With this information it might be possible to intervene with approved pharmacological treatments.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Preeclampsia

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * African-american or Caucasian * Pregnant * Between ages of 18 - 40 years of age Exclusion Criteria: * Presence of a disease or condition which is not preeclampsia * Drug or alcohol abuse during pregnancy * Obesity

Locations (1)

University of MS Medical Center

Jackson, Mississippi, United States

Outcomes

Primary Outcomes

Nitric oxide and Endothelin-1 levels

Time frame: 48 hours after tissue collection

Secondary Outcomes

Nitric oxide isoforms and Endothelin-1 receptor activation based on primary outcome

Time frame: within 6 months from tissue collection

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.