A Study of Pharmacokinetics and Safety of Alefacept in Caucasian and Japanese Healthy Volunteers

Inclusion Criteria: * Caucasian or Japanese healthy subject with a body mass index (BMI) of 18 to 29 kg/m2, inclusive * Japanese subject is first generation, born in Japan from parents of Japanese decent, and has resided outside of Japan for 5 years or less OR Caucasian subject is Hispanic or non-Hispanic, born of parents of European decent (not Mestizo or mixed race) * Subject must have clinical laboratory test results within the normal therapeutic range or, if abnormal, the results are not clinically significant as determined by the investigator Exclusion Criteria: * CD4+ lymphocyte count outside normal limits at Screening * Received vaccine within 60 days prior to study drug administration * History of drug or alcohol abuse within the 2 years prior to the study drug administration * Treatment with any systemic immunosuppressant agent within 6 months prior to study drug administration * Treatment with any antibody or biologic product within 6 months prior to study drug administration * Treatment with any systemic steroid or steroid inhaler within 2 months prior to study drug administration * A smoking habit of greater than 10 cigarettes a day