The aim of the present study was to compare the effect of unilateral versus bilateral stenting in patients with malignant hilar obstruction.
Cholangiocarcinoma accounts for 3% of all gastrointestinal cancers and is the second commonest primary liver cancer. However only a few patients are suitable for surgical resection and therefore endoscopic biliary drainage is the most used palliative treatment modality for malignant hilar stricture. However, whether one or two stents can benefit the patients most is still to be defined. Numerous retrospective case series reached different conclusion, till now, only one randomized trial compared the effect of unilateral versus bilateral stenting in patients with malignant hilar obstruction, nonetheless, nearly one third of the patients had Bismuth Type I stricture, and one stent is enough for drainage in this situation, therefore, the best drainage strategy for patients with Bismuth Type II or Bismuth Type III malignant hilar obstruction is unknown. The aim of the present study was to compare the effect of unilateral versus bilateral stenting in patients with Bismuth Type II or III malignant hilar obstruction.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
150
ERCP + one biliary stent insertion
ERCP + two biliary stents insertion
Changhai Hospital, Second Military Medical University
Shanghai, China
RECRUITINGDepartment of Surgery and Transplant Center
Astrova, Slovakia
RECRUITINGEarly complications
Time frame: 30 days within treatment
30-day mortality
Time frame: 30 days within treatment
Late complications
Time frame: 30 days after treatment
Median survival
Time frame: From stent insertion to the death of the patient
Successful drainage
Time frame: One month after stent insertion
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.