A Study Evaluating the Efficacy and Safety of Sildenafil in Patients With Erectile Dysfunction Receiving Hemodialysis

Inclusion Criteria: * Included patients had been in a stable relationship with a female partner for at least 6 months * A diagnosis of renal failure, with creatinine clearance ≤10 ml/min; been under hemodialysis for at least 6 months prior to the screening period, and a clinical diagnosis of erectile dysfunction (ED) as confirmed by International Index of Erectile Function (IIEF-5) score of \<21 and defined as an "incapacity to obtain and/or maintain an erection sufficient for a satisfactory sexual performance". Exclusion Criteria: * Patients in regular use of nitrates or nitric oxide donor drugs, or have received a prescription to use these substances in any formulation * Patients with genital anatomic malformation that may significantly impair erection (e.g., serious penile fibrosis) * Patients with other sexual disorders (e.g., hypoactive sexual desire) considered as a primary diagnosis, with a coexisting ED diagnosis, including patients receiving anti-androgenic therapy whose libido has not been preserved; patients receiving hormonal replacement therapy for at least 6 months, or whose dose has not been stabilized within the last 6 months before the study screening period * Patients with diabetes mellitus presenting poor control of their diabetes and/or proliferate diabetes retinopathy.