The Effect of Xolair (Omalizumab) on Allergy Blood Cells

Inclusion Criteria: * 2 year history of ragweed allergic rhinitis * positive skin prick tests to ragweed \>5 mm wheal diameter * serum IgE \<700 iU/m Exclusion Criteria: * Use of prohibited medications (e.g. antihistamine in past 7 days and topical or oral corticosteroids in past 1 month, beta-agonist or theophylline for 1 week * History of immunotherapy in the past 2 years * Exposure to Omalizumab in the past 2 years * Clinically significant non-allergic or perennial rhinitis to avoid mediator release due to environmental allergens * Asthma other than mild intermittent * Women of childbearing potential who are not on an accepted form of birth control, as well as women who are breastfeeding * Known sensitivity to study drug Xolair * Patients with severe medical condition(s) that in the view of the investigator prohibits participation in the study * Patients with a previous history of cancer * Use of any other investigational agent in the last 30 days