Amniotic Membrane and Anterior Stromal Puncture to the Treatment of Symptomatic Bullous Keratopathy

Federal University of São Paulo38 enrolled

Overview

The purpose of this study is to determine whether amniotic membrane transplantation is as effective as anterior stromal puncture in the relief of symptomatic bullous keratopathy.

Patients with symptomatic bullous keratopathy were randomized in 2 groups and submitted to amniotic membrane transplantation or anterior stromal puncture. The follow up was made with 1, 3, 6 and 12 months. Evaluation included complete ophthalmologic exam, esthesiometry, pachymetry, impression cytology and evaluation of pain.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Bullous Keratopathy

Interventions

amniotic membrane transplantationPROCEDURE

patients are submitted to amniotic membrane transplantation

anterior stromal puncturePROCEDURE

the other group is submitted to anterior stromal puncture

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * bullous keratopathy Exclusion Criteria: * age under 18 years old * asymptomatic bullous keratopathy * corneal infection * ocular hypertension

Locations (1)

Federal University of Sao Paulo

São Paulo, São Paulo, Brazil

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.