Multicenter Myocardial Viability Trial

CHI St. Luke's Health, Texas235 enrolled

Overview

The purpose of this study is to test the hypothesis of whether contrast enhanced Magnetic Resonance Imaging can be used to predict improvement of the wall motion in regions of the heart with abnormal movement following bypass surgery or percutaneous angioplasty in various institutions across three continents.

Study Type

OBSERVATIONAL

Enrollment

235

Conditions

Coronary Artery Disease

Eligibility

Sex: ALLMin age: 21 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age: \> 21 years and \< 85 years * Sinus rhythm * Weight \< 120 kg * LVEF \> 30% * Wall motion abnormality on Echo. or LV-gram * Scheduled for revascularization - Angioplasty/Stent or CABG - within 30 days Exclusion Criteria: * Resting heart rate \> 100 bpm * Frequent atrial or ventricular ectopy * Severe aortic stenosis or HOCM * Unstable angina * Myocardial infarction within 14 days * Active congestive heart failure * Pregnancy * Known allergy to gadolinium * Contraindication to MRI

Locations (7)

St. Luke's Episcopal Hospital

Houston, Texas, United States

St. Luke's Episcopal Location

Houston, Texas, United States

Cliniques Universitaires St. Luc

Brussels, Belgium

Skejby University Hospital

Aarhus N, Denmark

Outcomes

Primary Outcomes

To examine whether the extent of irreversible myocardial injury as assessed by Delayed Enhancement Magnetic Resonance Imaging can predict the extent of functional recovery after revascularization in patients with chronic coronary artery disease (CAD).

Time frame: 36 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.