Consequences of Hypoglycemia on Intensive Care Unit (ICU) Patients

University Hospital Muenster74 enrolled

Overview

Hypoglycemia occurs frequently during intensive blood glucose control in critically ill patients. The incidence of hypoglycaemia is associated with impaired outcome. However, it is hitherto unknown if hypoglycaemia itself predisposes patients to neurological impairment, e.g. cognitive dysfunction, or if it is the underlying medical condition that makes the patient prone to a high risk of hypoglycaemia and, concomitantly, neurocognitive impairment. Therefore we investigate neurocognitive function in patients who had hypoglycemias during their intensive care stay and compare the results to patients without hypoglycaemia whose medical conditions are matched to the hypoglycaemia patients.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Critical Illness

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * all patients Exclusion Criteria: * clinical diagnosis of diabetes mellitus * brain injury of any kind prior to or upon ICU-admission * pre-existing mental or psychiatric disorder * terminal kidney or liver failure prior admission * drug abuse, * CPR \> 5 min * HIV * Lues

Locations (1)

Department of Anesthesiology and Intensive Care, University Hospital Münster

Münster, Germany

Outcomes

Primary Outcomes

neurocognitive function

Time frame: 1 year after ICU discharge

Secondary Outcomes

neurocognitive function

Time frame: 2,3, and 4 years after ICU discharge