Matrix Metalloproteinase (MMP) in Heart Failure

Tottori University Hospital22 enrolled

Overview

The purpose of this study is to evaluate the production of MMP in failing hearts.

Myocardial fibrosis is observed in failing hearts and parallel to the progression of chronic heart failure (CHF) and myocardial remodeling. Matrix metalloproteinases (MMPs) are considered markers of fibrosis. Recently, circulating MMPs can be measured and are elevated in patients with CHF. However, MMPs it is still unclear whether MMPs are produced in failing hearts. Thus, the purpose of this study is to evaluate the production of MMP in failing hearts.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Chronic Stable Heart Failure

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * chronic stable heart failure

Outcomes

Primary Outcomes

MMPs level of coronary sinus

Data from ClinicalTrials.gov

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