Trial of Two Dosing Regimens of Micafungin Versus Caspofungin for the Treatment of Esophageal Candidiasis

Inclusion Criteria: * Esophageal candidiasis confirmed by endoscopy * Negative pregnancy test for female patients of childbearing potential Exclusion Criteria: * Pregnant or nursing female patient * Evidence of liver disease * Another active opportunistic fungal infection and/or receiving acute systemic therapy for an opportunistic fungal infection * Concomitant esophagitis caused by herpes simplex virus or cytomegalovirus * Received an oral or topical antifungal agent within 48 hours or a systemic antifungal agent within 72 hours of first dose of study drug * Known to be non-responsive to therapy in any prior systemic antifungal clinical trail * Experienced \> 2 episodes of esophageal candidiasis requiring systemic antifungal therapy * History of anaphylaxis attributed to echinocandin class of antifungals