Morphometric Analysis of Orbital Structures in Graves´ Orbitopathy

University of Sao Paulo80 enrolled

Overview

The purpose of this protocol is to study orbital structures in Graves´ Disease using multidetector computed tomography and color doppler imaging. Some changes in orbital structures detected by imaging exams could predict severity of the ocular Graves´disease. Thus the study could be useful in improve medical management of patients with Graves´ Disease.

Morphometric analysis of orbital structures in Graves´ Orbitopathy using multidetector computed tomography scan and color doppler imaging: Patients with Graves´ orbitopathy are evaluated by a complete ophthalmic examination.A prospective study with Multidetector CT scan and Color Doppler of these patients are made to develop parameters capable to predict Dysthyroid Optic Neuropathy (DON).

Study Type

OBSERVATIONAL

Enrollment

Conditions

Dysthyroid Orbitopathy

Eligibility

Sex: ALLMin age: 20 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Graves´Orbitopathy diagnosed based on previously reported criteria * Age above 20 years * Good cooperation for performing Visual Field test * Spherical refraction within ± 5 D and cylinder correction within ± 3 D Exclusion Criteria: * Graves´Orbitopathy not diagnosed

Locations (1)

General Hospital - University of Sao Paulo - School of Medicine

São Paulo, São Paulo, Brazil

Outcomes

Primary Outcomes

screening indexes for dysthyroid optic neuropathy

Time frame: indexes above 60% of orbital apex crowding were high suspected for DON

Data from ClinicalTrials.gov

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