Autologous Bone Marrow Transplant for Children With Acute Myelogenous Leukemia (AML) in First Complete Remission

Inclusion Criteria: * Patients aged between 1 and 18 years at diagnosis with acute nonlymphocytic leukemia in first remission are eligible for this protocol. * Patients enrolled on the AML-87 study in second or subsequent remission are eligible for this protocol. Exclusion Criteria: * Has an HLA-matched, MLC-compatible donor(unless parents and/or patient refuses transplant. * Diagnosis of FAB M3 or FAB M3v (acute progranulocytic leukemia) * Life expectancy limited by disease other than leukemia * Significant cardiac disease (echo shortening fraction \<25% or MUGA scan \<50%) * Severe renal dysfunction, i.e., creatinine clearance less than 60cc/1.73 m2/min * Severe restrictive pulmonary disease (FCV less than 40% of predicted) * Severe hepatic disease (bilirubin greater than 3 mg/dl or SGPT greater than 500IU) * Severe personality disorder or mental illness * Previous severe cystitis from cyclophosphamide * Previous total dose of anthracyclines of \>450 mg/m2 * Sever infection that on evaluation by the PI precludes ablative chemotherapy or successful transplantation * Previous autologous transplant * HIV reactivity * Karnofsky score \<70%