Efficacy and Safety of CIPRO XR Versus CIPRO IR in Patients With Complicated Urinary Tract Infections

Inclusion Criteria: The primary diagnosis in this clinical trial was cUTI in men or non-pregnant women over 18 years of age. Other main inclusion criteria: * One or more clinical symptoms and signs of a lower UTI: fever (\> 38°C, orally), chills, frequency of micturition, dysuria, urge sensation. * One or more of the following underlying conditions suggestive of cUTI: * Indwelling urinary catheter. * 100 mL of residual urine after voiding. * Neurogenic bladder. * Obstructive uropathy due to lithiasis, tumor or fibrosis. * Acute urinary retention in men. Exclusion Criteria: Diagnosis of pyelonephritis supported by clinical signs/symptoms of fever (\>38°C orally), chills and flank pain (all 3 signs/symptoms must be present). * Have a history of allergy to quinolones * Are unable to take oral medication * Have an intractable infection requiring \> 14 days of therapy * Have a requirement for concomitant administration of sucralfate or divalent and trivalent cations such as iron or antacids containing magnesium, aluminum or calcium * Have prostatitis or epididymitis * Have had a renal transplant * Have ileal loop or vesica- urethral reflux * Have significant liver or kidney impairment * Have a history of tendinopathy associated with fluoroquinolones * Are pregnant, nursing * Have a history of convulsions or CNS disorders