Wrist Cartilage - High Resolution in Vivo MR T2 Mapping- a Feasibility Study

Sheba Medical Center70 enrolled

Overview

Purpose:Evaluate the feasibility of T2 cartilage mapping on MRI of the wrist and correlate with T2 mapping of knee cartilage. Study protocol: Phase 1. 10 healthy volunteers, Phase 2. 10 volunteers with osteoarthritis of the wrist, Phase 3. 50 patients for studies for routine MR of the wrist. MRI protocol: 3 T unit((Signa EXITE HDx),T1, T2 and T2 mapping sequences on axial and coronal orientation.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Osteoarthritis

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Phase 1. Age:18-40 * Phase 2: No age limit, known OA on pre-existing X-rays * Phase 3: No age limit, routine MRI of the wrist Exclusion Criteria: * Phase 1, 2: wrist trauma/surgery * All phases: any contraindication for MR: eg metals, claustrophobia, etc.

Locations (2)

Sheba Medical Center , Diagnostic Imaging Dept

Tel Litwinsky, Tel Hashomer, Israel

RECRUITING

Sheba Medical Center, Diagnostic Imaging Dept

Tel Litwinsky, Tel Hashomer, Israel

ENROLLING_BY_INVITATION

Outcomes

Primary Outcomes

wrist bone cartilage thickness can be measured and stratification can be observed on T2 mapping with correlation to T2 mapping of the knee cartilage

Time frame: Within MRI completion (20 minutes)

Data from ClinicalTrials.gov

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