Supplemental Perioperative Oxygen to Reduce the Incidence of Post-Cesarean Endometritis and Wound Infection

University of Washington143 enrolled

Overview

The purpose of this study is to determine whether supplemental perioperative oxygen significantly decreases the incidence of post-Cesarean endometritis and wound infection among women who undergo Cesarean section after the onset of labor.

Women undergoing cesarean section after rupture of membranes or onset of labor are randomized in a one to one ratio to either normal or supplemental perioperative oxygen during cesarean section and for two hours afterwards.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

143

Conditions

Wound Infection or Endometritis Post Cesarean Section

Interventions

supplemental perioperative oxygenPROCEDURE

increased perioperative oxygen verses non-interventional oxygen

Eligibility

Sex: FEMALEMin age: 16 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Women who underwent a clinically indicated cesarean delivery after the onset of labor or rupture of membranes Exclusion Criteria: * Cesarean delivery prior to the onset of labor or rupture of membranes * emergent cesarean delivery * general endotracheal anesthesia * clinical chorioamnionitis * HIV infection * less than 16 years of age

Outcomes

Primary Outcomes

surgical site infection

Time frame: within two weeks of cesarean section

Data from ClinicalTrials.gov

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