This study will look at how pacing your heart may assist your daily activities and how you are feeling.
RESET is a multicenter trial that will assess the effect of pacing in heart failure patients with a normal ejection fraction (or diastolic heart failure). The purpose of the RESET study is to evaluate the effect of pacing on exercise capacity and quality of life in this heart failure population.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
32
Cardiac pacing using any Guidant/Boston Scientific Implantable Pacemaker System with rate-modulation and any compatible intracardiac lead system.
Cardiovascular Associates of Northeast Arkansas
Jonesboro, Arkansas, United States
Cardiovascular Associates
Louisville, Kentucky, United States
Johns Hopkins Medical Institutions
Baltimore, Maryland, United States
Mayo Clinic Foundation
Rochester, Minnesota, United States
Peak Volume of Oxygen Uptake (Peak VO2) - Rate Adaptive Pacing (RAP) On at One Month vs. Rate Adaptive Pacing (RAP) Off at One Month.
Randomized therapy order cross-over comparison at 1 month post-implant. Each patient evaluated for endpoint with and without RAP therapy at this time.
Time frame: 1 month post implant
Peak Volume of Oxygen Uptake (Peak VO2) - Rate Adaptive Pacing (RAP) On at Six Months vs. Rate Adaptive Pacing (RAP) Off at One Month.
Each patient had RAP therapy On from one through six months. This endpoint evaluated Peak VO2 measured at 6 months (RAP On) vs. Peak VO2 measured at 1 month without RAP therapy (RAP Off).All participants were "RAP On" for months 1 through 6. All participants were 'Rap On' for months 6 to 12.
Time frame: 6 months post implant
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Tyler CV Consultants - Trinity Mother Frances
Tyler, Texas, United States