Sinus surgery is a common, day surgery procedure performed by general and subspecialty trained otolaryngologists. In most cases, this is a safe surgery with a low incidence of complications. When there is significant bleeding or enough bleeding to obscure important anatomical landmarks, there is a higher chance of complications. These complications can include blindness, meningitis or cerebrospinal fluid leak. Our hypothesis is that in patients taking oral tranexamic acid three days before surgery and six days after, there will be less intraoperative bleeding, better surgical visualization and less postoperative bleeding events.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
74
Oral form, 100mg, tid (three times per day), 3 days before/the day of/6 days after the surgery
Placebo, Oral form, three times a day, 3 days before/day of/6 days after surgery
Rockyview General Hospital
Calgary, Alberta, Canada
Intraoperative bleeding amount
Time frame: During the surgery
Surgical visualization scoring
Time frame: During the surgery
Postoperative bleeding events
Time frame: Six days after the surgery
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