The purpose of this study is to determine whether Extract of Ginkgo Biloba is effective in the treatment on Tardive dyskinesia
Tardive dyskinesia(TD) is a common complication of conventional antipsychotic treatment in subjects with schizophrenia. There is no established treatment for TD patients.This disorder remains a significant clinical problem for both patients and physicians for the foreseeable future.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
157
EGb-761 240mg/d, 1 capsule(80mg) tid,po,12 weeks; Each capsule contains 19.6mg flavonol glycosides and 4.8mg terpene lactones.
Wheat flour placebo capsule,1 capsule tid, po,12 weeks
Beijing Hui-Long-Guan Hospital
Beijing, China
Change in the scores of Abnormal Involuntary Movement Scale (AIMS)
Time frame: Baseline, 6th and 12th week
Change in PANSS
Time frame: Baseline, 6th and 12th week
Change in Simpson-Angus Rating Scales for EPS
Time frame: Baseline, 6th and 12th
Change in cognitive function
Time frame: Baseline and 12th week
Change in Udvalg for Kliniske Undersøgelser (UKU) Side Effect Rating Scale
Time frame: Baseline, 6th and 12th week
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