Protocol to Assess the Severity of Acute Kidney Injury

Inclusion Criteria: * 18 years and older * Increase in serum creatinine of 0.3 mg/dl within 48 hours or an increase of greater or equal to 150 to 200% from baseline or sustained oliguria(mean urine output of \<0.5 cc/kg/hr for 6 hours within 48 hours) * Written informed consent * Patients who already have a indwelling bladder catheter Exclusion Criteria: * Voluntary refusal or missing written consent of the patient or the designated legal representative * Patients with advanced Chronic Kidney Disease - as defined by a baseline GFR of \< 30 ml/min as calculated by the MDRD equation * Patients with renal transplantation * Pregnancy * Patients with an allergy or sensitivity to loop diuretics * Patients with a clinical syndrome consistent with pre-renal AKI * Defined by fractional excretion of Na of \< 1% AND no evidence of the urinary casts, or * Patients that are under-resuscitated as deemed by treating clinical team or * Patients who are actively bleeding * Patients with a clinical syndrome of post-renal AKI * Any radiological study that shows hydro-ureter, or * Clinical scenario wherein the obstruction is considered a likely possibility of the cause of AKI