Use of Amnion on Partial Thickness Burns

The University of Texas Medical Branch, Galveston

Overview

To determine if Amnion, used on partial thickness burn injuries would provide an improvement in rate of healing, pain control and scarring as compared to standard medical treatments.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Conditions

Burn

Interventions

AmnionBIOLOGICAL

Application of Amnion with processing procedures involving the use of trypsin-EDTA

AmnionBIOLOGICAL

Application of Amnion with processing procedures involving the use of Dispase II

Polysporin/Bacitracin/MycostatinDRUG

Application of Prepared antibiotic ointment: Polysporin, Bacitracin and Mycostatin combined

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Partial thickness burn injury. * \>2% burn injury. * Ages 0-100 years. Exclusion Criteria: * Patients not expected to survive

Outcomes

Primary Outcomes

Length of time to 95% healing of treated burn wounds

Time frame: Assessment daily until 95 % healed

Secondary Outcomes

Length of hospital stay

Time frame: Measured at hospital discharge

Incidence of infection

Time frame: Measure daily until complete wound healing

Amount of daily pain until wound is healed with different treatments.

Time frame: Daily until wound is completely healed.

Amount of scaring with different treatments

Time frame: From injury to 2 years post burn

Data from ClinicalTrials.gov

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