The purpose of the study is to determine whether thrombus removal with aspiration thrombectomy for acute myocardial infarction reduces the infarct size.
Acute myocardial infarction is caused by an abrupt occlusion of coronary vessel or severe reduction of coronary flow. It has been shown that the reperfusion therapy significantly improves the clinical outcome. Currently the optimal strategy is the primary angioplasty with stent implantation. The treatment is recommended by AHA/ACC and ESC if can be performed within 90 minutes from the first medical contact. However there is still a certain percentage of procedure failure. To further improve the outcome new techniques and devices are tested . Aspiration thrombectomy may facilitate the reperfusion by reducing thrombus burden. The aim of the study is to assess if adjunctive thrombectomy may improve clinical outcome in patients with an acute ST segment elevation myocardial infarction.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
140
Aspiration Thrombectomy prior to stent implantation in patients with ST segment elevation myocardial infarction
Standard primary angioplasty with stent implantation
Institute of Cardiology
Warsaw, Poland
Myocardial salvage index assessed with SPECT MIBI.
Time frame: 5-8 days
In hospital mortality
Time frame: in hospital, before discharge
ST segment resolution after PCI;
Time frame: 90 minutes
CK-MB AUC
Time frame: 72 hours
Corrected TIMI frame count
Time frame: immediately post PCI
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