Drug-Drug Interaction Study of Esomeprazole (D961H) Capsule and Loxoprofen Tablet After Repeated Oral Administration in Japanese Males

Inclusion Criteria: * Healthy Japanese male * Body Mass Index (BMI=weight/height2) 19-27 (kg/m2) * Body weight 50-80 kg Exclusion Criteria: * Past or present NSAIDs induced asthma, hepatic dysfunction, peptic ulcer or blood disorders * Significant clinical illness from the 2 weeks preceding the pre-entry visit to the randomisation, as judged by the investigator(s) , eg, acute inflammatory disease which requires medical intervention * Past or present cardiac, renal, hepatic, neurological or gastrointestinal disease, as judged by the investigator(s), eg, sequelae of myocardial infarction, nephritis, hepatitis and cerebral infarction