The Acute Effect of Atorvastain on Renal Function in Patients With Type II Diabetes

Inclusion Criteria: 1. Age: 40-70 yrs 2. estimated GFR between 30 and 90 ml/min 3. BMI\<35 4. Fertile women had to use oral contraceptives or IUD 5. HbA1c\< 10% 6. Urine-albumin\<1,5 g/l Exclusion Criteria: 1. Treatment with insulin 2. Cerobrovascular insult or other disease of the brain 3. Insufficiency of the heart or lungs 4. Liverdisease with ALAT \> 200 U/L 5. hemoglobin \< 7,0 mmol/l 6. Cancer 7. Alcohol abuse 8. Medical treatment with psycopharmaca or/and analgetics 9. Pregnancy and breast feeding, 10 blood donation one month before the study.