The objective of this study is to evaluate the safety and efficacy of the combination of ABT-335 plus rosuvastatin in dyslipidemic subjects with Chronic Kidney Disease (CKD) Stage 3.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
280
ABT-335 45 mg plus rosuvastatin 5 mg for 8 weeks, then ABT-335 45 mg plus rosuvastatin 10 mg for 8 weeks
Rosuvastatin 5 mg for 8 weeks then rosuvastatin 10 mg for 8 weeks
Median Percent Change in Triglycerides From Baseline to Week 8.
Triglycerides were measured in milligrams/deciliter.
Time frame: Baseline to 8 weeks
Mean Percent Change in High-Density Lipoprotein Cholesterol From Baseline to Week 8.
High-density lipoprotein cholesterol (HDL-C) was measured in milligrams/deciliter (mg/dL).
Time frame: Baseline to 8 weeks
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Site Reference ID/Investigator# 22521
Birmingham, Alabama, United States
Site Reference ID/Investigator# 22478
Huntsville, Alabama, United States
Site Reference ID/Investigator# 8365
Madison, Alabama, United States
Site Reference ID/Investigator# 8416
Montgomery, Alabama, United States
Site Reference ID/Investigator# 7869
Chula Vista, California, United States
Site Reference ID/Investigator# 8435
Fountain Valley, California, United States
Site Reference ID/Investigator# 22487
Lincoln, California, United States
Site Reference ID/Investigator# 22426
Long Beach, California, United States
Site Reference ID/Investigator# 8096
Los Angeles, California, United States
Site Reference ID/Investigator# 22962
Norwalk, California, United States
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