The purpose of this study is to determine the cumulative irritation potential of the products listed by the Sponsor.
Healthy, adult volunteers of either sex will be patched on his/her back with AN2690 Solution 2.5%, AN2690 Solution 5%, AN2690 Solution 7.5%, AN2690 Solution Vehicle and Sodium Laurel Sulfate 0.5% over the course of 21 consecutive days. After 24 hours, the patches are to be removed and the site evaluated using a five-point scale for irritation.
Study Type
INTERVENTIONAL
Purpose
OTHER
Masking
NONE
Enrollment
37
The Education and Research Foundation, Inc.
Lynchburg, Virginia, United States
Severe irritation (Grade 3 or 4) observed at any site
Time frame: Daily for 21 days
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AN2690 Solution, Vehicle, Daily for up to 21 days
Sodium Lauryl Sulfate, 0.5%, Daily for up to 21 days