Safety Study of Subcutaneous Ig NextGen 16% in Patients With Primary Immunodeficiency

Inclusion Criteria: 1. Age \>3 years of age. 2. PID patients receiving Ig replacement therapy. 3. Patients must have completed or withdrawn from CSLCT-SCIG-05-23 and wish to continue SCIg therapy; or, patients ineligible for CSLCT-SCIG-05-23 but for whom the Investigator believes SCIg may be a suitable form of Ig replacement, for reasons such as: poor tolerability of IVIg, difficult venous access, or, preferred route of administration. 4. Patient is capable of self-administering Ig NextGen 16% Exclusion Criteria: 1. Patients eligible for CSLCT-SCIG-05-23 if still open for recruitment. 2. Patients with known anaphylaxis reactions to immunoglobulin therapy. 3. Patients with known selective IgA deficiency or antibodies to IgA with a history of reactions to Ig therapy. 4. Patients with protein-losing enteropathies. 5. Patients who are suffering from an acute or chronic medical condition, other than PID, which may, in the opinion of the Investigator, affect their treatment or the conduct of the trial. 6. Females who are pregnant, breast feeding or planning a pregnancy during the course of the study. Females who are of child bearing potential must have a negative pregnancy test at screening. 7. Patients unwilling to comply with the protocol.