To verify the number of metastatic brain tumors detected in contrast-enhanced MRI, which is the primary variable, increases after an additional dose of Magnevist (SH L 451A) comparing images after an initial dose (0.1 mmol/kg) with those after an additional dose (0.1 mmol/kg, a total dose of 0.2 mmol/kg) intra-individually in patients with metastatic brain tumors. Safety was also to be assessed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
45
Magnevist at a dose of 0.1 mmol/kg
Magnevist at a dose of 0.1 mmol/kg and another 0.1 mmol/kg 30minutes later.
Unnamed facility
Yokohama, Kanagawa, Japan
Unnamed facility
Osaka, Osaka, Japan
Unnamed facility
Osaka, Osaka, Japan
Unnamed facility
Hamamatsu, Shizuoka, Japan
Diagnostic ability
Time frame: MRI image in blinded read
Visibility
Time frame: MRI image in blinded read
Diagnostic confidence
Time frame: MRI image in blinded read
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Unnamed facility
Bunkyo-ku, Tokyo, Japan
Unnamed facility
Ōta-ku, Tokyo, Japan
Unnamed facility
Shinagawa-ku, Tokyo, Japan
Unnamed facility
Shinjuku-ku, Tokyo, Japan
Unnamed facility
Nakakoma-gun, Yamanashi, Japan