Insulin Sensitivity and Substrate Metabolism in Patients With Cushing's Syndrome

N/ATerminatedNCT00682084

University of Aarhus1 enrolled

Overview

The purpose of this study is to investigate the effect og chronic elevated levels of cortisol on metabolism and insulin sensitivity.

Study Type

OBSERVATIONAL

Enrollment

SurgeryPROCEDURE

Surgical removal of either a pituitary or ectopic ACTH producing tumor or an adrenal tumor

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Written consent * Age between 18 and 70 * Diagnosed with Cushing's syndrome Exclusion Criteria: * Suspected malignancy

Department of Endocrinology

Aarhus C, Aarhus, Denmark

Insulin sensitivity

Time frame: Before and after treatment

Glucose tolerance, QoL, body composition, intrahepatic and intramyocellular fat, substrate metabolism.

Time frame: Before and after treatment

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