A Comparison of SmartPill Capsule With Scintigraphy for Determining Gastric Residence Time - Over 65 Years Old

Inclusion Criteria: * Inclusion Criteria For Healthy Subjects: * Healthy males and females between ages 65-80 years of age with no gastrointestinal disease as screened by the GI Disease Screening Questionnaire * Average bowel movement frequency of at least one bowel movement within 48 hours * Subjects with high probability for compliance and completion of the study * Inclusion Criteria For Subjects with Gastroparesis: * Abnormal gastric emptying as defined by local standards and documented by nuclear medicine scintigraphy performed within the last two years. * Males and females between ages 18-65 years of age. * Average bowel movement frequency of at least one bowel movement within 72 hours * Subjects with high probability for compliance and completion of the study * Upper endoscopy or upper GI within last 3 years showing no evidence of gastric bezoar, stricture, or peptic ulcer. Exclusion Criteria: * Exclusion Criteria For Healthy Subjects: * Prior GI surgery * Surgery within the past 3 months * Diverticulitis * Tobacco use within eight hours prior to capsule ingestion and during the 8 hour monitoring time. * Alcohol use within 24 hours prior to capsule ingestion and throughout the entire monitoring period (up to 72 hours). * Body mass index (BMI) \> 35 * Allergies to components of the test meal including eggs, bread, and jam. * Female of childbearing age who is not practicing birth control and/or is pregnant or lactating. (Confirm with urine pregnancy test) * Cardiovascular, endocrine, renal, or other chronic disease likely to affect motility. * Exclusion Criteria For Subjects with Gastroparesis: * History of gastric bezoar * Severe dysphagia to solid food and pills * Severe vomiting more than 1 time per day * Diverticulitis * Severe daily abdominal pain requiring medications for relief * Severe weight loss, greater than 10 lbs over the preceding 2 months. * Uncontrolled diabetes with a hemoglobin A1C greater than 10. * Excessively delayed gastric emptying time: more than 90% of a standard egg meal retained after 2 hours. * Previous gastro-esophageal surgery including vagotomy, fundoplication, gastric bypass, ulcer surgery. * Prior GI surgery except for uncomplicated appendectomy and laparoscopic cholecystectomy * Surgery within the past 3 months * Tobacco use within eight hours prior to capsule ingestion and during the 8 hour monitoring time. * Alcohol use within 24 hours prior to capsule ingestion and throughout the entire monitoring period (up to 72 hours). * BMI \> 35 * Allergies to components of the test meal including eggs, bread, and jam * Female of childbearing age who is not practicing birth control and/or is pregnant or lactating. (Confirm with urine pregnancy test)