Effect of Choline Fenofibrate (SLV348) on Macular Edema

Inclusion Criteria * With DME in at least one eye of the subject and this eye presenting with macula thickness ≥ 300 µm on OCT examination at baseline in at least one of the 5 following zones: center zone, or superior inner zone, or nasal inner zone, or inferior inner zone, or temporal inner zone, confirmed after central reading of the OCT; * When laser treatment can be safely postponed by up to at least 3 months; * With established T2DM and HbA1c \< 10%; * With systolic blood pressure (SBP) or diastolic blood pressure (DBP) \< 160/90 mmHg; * With documented elevated triglyceride levels (TG \>=150 mg/dL \[1.70 mmol/L\]) at the screening visit or in the previous 3 months. Exclusion Criteria * Previous laser photocoagulation; * Eye retinal thickening results from epiretinal membranes or vitreomacular traction; glaucoma; * Poor visual acuity: visual acuity of 20/800