Safety, Efficacy, and Pharmacokinetic Profile of DNB-001 in Subjects With Elevated Intraocular Pressure

Inclusion Criteria: * Male or female, at least 18 years old, in general good health, not presently treated for elevated intraocular pressure (IOP), with best corrected Early Treatment Diabetic Retinopathy Study (ETDRS) visual acuity score equivalent to a Snellen score of 20/50 or better in each eye and lOP of 21 to 29 mm Hg at baseline. Exclusion Criteria: * Use of intraocular pressure lowering medication within the past 3 months or any history of ocular surgery for glaucoma * Evidence of potential angle closure by gonioscopy * Abnormal optic disc or visual field consistent with glaucoma * Use of topical ocular medications during the study and any evidence of systemic disease that might interfere with the conduct of the study.