Comparison of various antibiotics in treatment of uncomplicated pelvic inflammatory disease
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
749
Ofloxacin 400 mg po bid plus metronidazole 500 mg po bid for 14 days
Moxifloxacin 400 mg po od for 14 days
Clinical response 5 to 24 days after the last dose of study medication
Time frame: 5 to 24 days after the last dose
Bacterial response at the test of cure visit and at the FU visit 28 to 42 days after last dose of study medication
Time frame: visit 28 to 42 days after last dose
Clinical response at during-treatment visit (Day 4-7) and at follow-up 28 to 42 days after last dose
Time frame: (Day 4-7) and at follow-up 28 to 42 days after last dose
Reduction from baseline in pain report at the different assessment visits
Time frame: Over the entire trial period (overall)
Necessity for modifying antibiotic therapy at the during-treatment visit and TOC visit and necessity for institution of an antibiotic therapy at follow-up
Time frame: Over the entire trial period (overall)
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Unnamed facility
Hvidovre, Denmark
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Odense C, Denmark
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Roskilde, Denmark
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Hämeenlinna, Finland
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Helsinki, Finland
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Joensuu, Finland
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Kotka, Finland
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Antony, France
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Beaumont, France
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Bordeaux, France
...and 67 more locations