Palonosetron in Moderately and Highly Emetogenic Chemotherapy Induced Nausea and Vomiting (Study P04935)(COMPLETED)

Inclusion Criteria: * Patients must be 18 years of age or older. * Histological or cytological confirmation of malignant disease. * Karnofsky index \>= 50% * Naïve to chemotherapy (First Cycle of chemotherapy IV with moderate or high emetic risk administered during Day 1 of the study, according to modification of the classification of Paul Hesketh's schema published on Annals of Oncology 17: 20-28, 2006 (Appendix 3). * Patients that voluntarily sign the consent form. Exclusion Criteria: * Pregnancy or suspected. * Patients during breast feeding. * Inability to understand or cooperate with the study procedures. * Received any investigational drugs within 30 days before study entry. * Received any drug with potential anti-emetic efficacy within 24 hours prior to the beginning of the treatment * Seizure disorders requiring anticonvulsant medication. * Persistent vomiting due to any organic etiology. * Experienced any vomiting, nausea or retching, in the 24 hours prior to chemotherapy. * Any systemic disease different to base disease * Known current or history of drug or alcohol abuse * Gastric outlet or intestinal obstruction