Cerebellar Loops and Attention Deficit Hyperactivity Disorder (ADHD)

University Hospital, Bordeaux19 enrolled

Overview

The aim of this study is to investigate the integrity of connectivity between the neocortex and the cerebellum in the Attention Deficit Hyperactivity Disorder (ADHD). Fibers integrity will be measured using magnetic Resonance Imaging Techniques.

ADHD is a neurodevelopmental trouble characterized by attentional deficits, impulsivity and motor hyperactivity. Morphological neuroimaging studies in ADHD children have revealed cerebellar abnormalities, however data in adults regarding cerebellum alterations are scarce. In this study we will analyse the conectivity of the cerebellum of adults ADHD patients. We will use diffusion tensor imaging (DTI) technique, and morphological data will be compared with the neuropsychological status.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Attention Deficit Disorder With Hyperactivity

Interventions

ImagingOTHER

neuropsychological evaluation and Imaging with magnetic resonance (MRI)

Eligibility

Sex: ALLMin age: 18 YearsMax age: 35 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Patient with ADHD : * Diagnosis of ADHD * 18 - 35 years old Healthy volunteer : * 18 - 35 years old * no ADHD diagnosed Exclusion Criteria: * Associated neurological or psychiatric pathologies * Pregnant woman * MRI counter indication

Locations (2)

Charles Perrens Hospital

Bordeaux, France

University Hospital Bordeaux

Bordeaux, France

Outcomes

Primary Outcomes

Fractional anisotropy coefficient if fronto-cerebello-frontal loops.

Time frame: visite 1

Data from ClinicalTrials.gov

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