Wingspan Stenting for Symptomatic Severe Stenosis of Intracranial Atherosclerosis Registry in China

Inclusion Criteria: * An angiographically verified ≥ 70% stenosis of a major intracranial artery that causes TIA or minor stroke (NIH Stroke Scale score \<9) within 90 days; * the lesion length \<15 mm and normal arterial diameter adjacent to it between 2.0 mm and 4.5 mm; * patients having at least one atherosclerotic risk factor (arterial hypertension, diabetes mellitus, hyperlipidemia, hyperhomocysteinemia and cigarette smoking). Exclusion Criteria: * Non-atherosclerotic stenosis; * intracranial hemorrhage in the territory of the stenotic artery within 6 weeks; potential source of cardiac embolism; * concurrent intracranial tumor, aneurysm and cerebral arteriovenous malformation; * tandem \>50% stenosis of extracranial carotid or vertebral artery; known contraindication to heparin, aspirin, clopidogrel, anesthesia and contrast media; hemoglobin \<10 g/dl, platelet count \<100,000; * international normalized ratio \>1.5 (irreversible) and uncorrectable bleeding diathesis; and life expectancy \<1 years because of other medical conditions.