AZD6140 Oral Contraceptive Interaction Study

Inclusion Criteria: * Females who are healthy, non-pregnant, not planning pregnancy within the study period, non-breast-feeding, and pre-menopausal * Either currently taking Nordette® which was well tolerated for at least two months prior to randomisation with no history of break-through bleeding, or, willing to take Nordette for 2 months prior to receiving the study drug * Females of child-bearing potential must be willing to use at least 1 additional medically approved non-hormonal barrier contraceptive method (for example, condom or diaphragm) that contains spermicide Exclusion Criteria: * History of intolerance (e.g. adverse events) to any oral contraceptive or AZD6140 * History of blood vessel or bleeding conditions that would make the volunteer more prone to bleeding * History or presence of significant medical problems * Women who are current smokers