Pegylated Interferon (PEG-IFN) Alfa-2b and Low Dose Ribavirin for the Treatment of Chronic Hepatitis C Patients With Genotype 1 High Viral Load and Low Body Weight (Study P05172)(COMPLETED)

Inclusion Criteria: * Diagnosed with chronic hepatitis C. * Minimum 20 years of age * Willing to use adequate contraception during the course of the study. * Participants who can be hospitalized for at least 14 days since treatment initiation. * Positive for HCV genotype 1 (genotype 1a and 1b) with high viral load (HCV-RNA \>=100 kIU/mL). * Participants weighing over 40 kg to 50 kg. * Hematology results of: * hemoglobin levels \>=12 g/dL * neutrophils \>=1,500/mm\^3 * platelets \>=100,000/mm\^3 Exclusion Criteria: * Previous ribavirin therapy. * Previous interferon therapy within 90 days of registration. * Participants who received treatment with injectable products containing glycyrrhizin/cysteine/glycine (Stronger Neo-Minophagen C, etc.), Shosaikoto, or ursodeoxycholic acid within 30 days before the start of treatment * Participants who received treatment with an antiviral or anti-tumor drug or who received immunomodulating therapy (including steroids and radiotherapy) within 90 days before the start of treatment \[excluding local administration and topical drugs\]. * Participants who received other investigational drugs within 180 days before the start of treatment. * Hepatitis Bs (HBs) antigen-positive * Antinuclear antibodies \>=1:160 * Fasting blood glucose \>=110 mg/dL (however, participants with fasting blood glucose of 110 mg/dL to \<126 mg/dL can be registered if HbA1c is \<6.5%) * Participants diagnosed with liver cirrhosis in most recent celioscopy or liver biopsy. * Participants with or who have a history of any of the following: liver failure; hepatic encephalopathy, esophageal varices, or ascites; depression or schizophrenia requiring treatment or suicidal attempt or ideation; epileptic seizures requiring drug treatment; autoimmune disease (such as Hashimoto's disease, Crohn's disease, ulcerative colitis, chronic rheumatoid arthritis, idiopathic thrombocytopenic purpura, systemic erythematosus, autoimmune hemolytic anemia, and scleroderma); hepatic cancer * Participants with any of the following: liver disease such as autoimmune hepatitis, alcoholic liver disease, and drug-induced hepatic impairment; hemophilia; arrhythmia requiring treatment and participants with or who have a history of angina pectoris, cardiac failure, myocardial infarction, or life-threatening arrhythmia; hypertension (systolic BP of 160 mmHg or more and diastolic BP of 100 mmHg or more) not possible to control with drug therapy; chronic pulmonary disease; hemoglobinopathy (thalassemia, sickle cell anemia); malignant tumor or who have a history of malignant tumor within the past 5 years; thyroid function disorder not controlled by drug therapy. * Participants with organ transplants (excluding cornea and hair transplants). * Participants with a history of hypersensitivity to interferon preparations, nucleoside analogs, or biological products such as vaccine. * Participants with a specific response to PEG-IFN alfa-2b in a prick test to be conducted just before the initiation of treatment. * Participants who are pregnant or nursing (in the case of male Participants : partner is pregnant)