Fed Bioavailability Study of Zonisamide Capsules

Inclusion Criteria: * Screening Demographics: * All volunteers selected for this study will be healthy men and women 18 years of age or older at the time of dosing * Weight range will not exceed ± 20% for height and body frame * Screening Procedures: Each volunteer will complete the screening process within 28 days prior to Period I dosing * Consent documents for both the screening evaluation and HIV antibody determination will be reviewed, discussed, and signed by each potential participant before full implementation of screening procedures * Screening will include general observation, physical examination, demographics, medical and medication history, an electrocardiogram, sitting blood pressure and heart rate, respiratory rate and temperature * The physical examination will include, but may not be limited to, an evaluation of the cardiovascular, gastrointestinal, respiratory and central nervous systems * The screening clinical laboratory procedures will include: Hematology, Clinical Chemistry, HIV antibody, Hepatitis B surface antigen, Hepatitis C antibody, Urinalysis, Urine Drug Screen, Serum Pregnancy Screen, Follicle Stimulating Hormone * If female: postmenopausal for 1 year or surgically sterile. Exclusion Criteria: * Volunteers with a recent history of drug or alcohol addiction or abuse * Volunteers with the presence of a clinically significant disorder involving the cardiovascular, respiratory, renal, gastrointestinal, immunologic, hematologic, endocrine, or neurologic system(s) or psychiatric disease * Volunteers whose clinical laboratory test values are outside the accepted reference range and when confirmed on re-examination are deemed to be clinically significant * Volunteers demonstrating a reactive screen for hepatitis B surface antigen, hepatitis C antibody or HIV antibody screen * Volunteers demonstrating a positive drug abuse screen when screened for this study * Female volunteers demonstrating a positive pregnancy screen * Female volunteers who are currently breastfeeding * Volunteers with a history of allergic response(s) to zonisamide or related drugs * Volunteers with a history of clinically significant allergies including drug allergies * Volunteers with a clinically significant illness during the 4 weeks prior to Period I dosing (as determined by the clinical investigator) * Volunteers who currently use tobacco products * Volunteers who have taken any drug known to induce or inhibit hepatic drug metabolism in the 28 days prior to Period I dosing * Volunteers who report donating greater than 150mL of blood within 28 days prior to Period I dosing. All subjects will be advised not to donate blood for four weeks after completing the study * Volunteers who report receiving any investigational drug within 14 days prior to Period I dosing. * Volunteers who have donated plasma(e.g. plasmapheresis) within 14 days prior to Period I dosing. All subjects will be advised not to donate plasma for four weeks after completing the study * Volunteers who report taking any systemic prescription medication in the 14 days prior to Period I dosing.