Infusion of a Single Dose of Erythropoietin to Prevent Injury in an Ischemia Reperfusion Forearm Model

Inclusion Criteria: * Healthy volunteers between 18 and 40 years of age * male * Volunteers are not allowed smoking 24 hours before the start of the experiment Exclusion Criteria: * Female * Hypertension (SBP \>140 mmHg, DBP \>90 mmHg) * Diabetes Mellitus (DM) (fasting glc \>6.9 mmol/l, glc \>11.0 mmol/l) * Hypercholesterolemia * Renal dysfunction (eGFR \< 60 ml/min, calculated using MDRD formula) * Any known hypersensitivity/allergic reaction to one of the constituents of Epoetin Alfa * A history of use of any form of EPO * Any current medication use * Cardiovascular disease in medical history * Smoking less than 24 hours prior to Epoetin alpha infusion * Participation in research in the last 5 years in which any form of radioactivity was used * No participation in any research trial in the last 30 days or 5 times the half-life of the used substance