Evaluate effect of application procedure on efficacy of 2 antiseptics for cleaning skin prior to surgery.
Evaluate the effect of application procedure on the antimicrobial properties of a new product and a currently marketed product. Study will be conducted using methods dictated by the FDA. Study uses topical sampling from the abdomen and groin on intact skin and evaluates the germs. Effects of blotting versus not blotting will be assessed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
122
Chlorhexidine gluconate (2% w/v) in an aqueous base. Administered topically.
Povidone iodine scrub and paint. Administer topically.
BioScience Laboratories
Bozeman, Montana, United States
3.0 log10 reduction in CFU/cm2 on inguinal sites, and 2.0 log10 reduction in CFU/cm2 on abdominal sites
Time frame: 10 minutes and 6 hours after application of test solutions
Impact of blotting versus not blotting
Time frame: Blotting and not blotting after 2 minute application with CHG and 5 minute application of iodophor
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