This study will compare a high-protein/low-carbohydrate diet (modified paleolithic diet, MPD) with a diet high in slow carbohydrates (Nordic Nutrition Recommendations, NNR). The diets will be compared with respect effects on weight reduction, metabolic regulation, and long-term compliance to the diet regimes. Seventy-two postmenopausal overweight healthy women have been recruited and will be followed for two years. The following variables will be studied: * Anthropometry * DEXA * OGTT * Liver fat content measured with 1H-MRS * Hepatic 11β-HSD1 activity, measured with cortisone/cortisol conversion test
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
NONE
Enrollment
70
Diet with equal amounts of fat, protein and carbohydrates
A diet high in protein and fat, but low in carbohydrates
Umeå University
Umeå, Sweden
Liver fat
Time frame: Sept 2008
Body weight
Time frame: Sept 2008
Apnea-Hypopnea Index (AHI)
Time frame: Sept 2008
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