Survival Study in Patients Undergoing On-line Hemodiafiltration

Hospital Clinic of Barcelona906 enrolled

Overview

Patients on hemodialysis will be randomly assigned (1:1) to continue on conventional hemodialysis or on-line hemodiafiltration, both three times per week. A 3 year follow-up and a sample size of around 750 will be necessary to detect a 35% reduction in mortality.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

906

Conditions

Hemodialysis

Interventions

HemodialysisPROCEDURE

3 times per week

On-line hemodiafiltrationPROCEDURE

3 times per week

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18 and older * Currently undergoing hemodialysis * Clinical stability * Stable vascular access Exclusion Criteria: * Chronic inflammatory diseases * Liver cirrhosis * Malignancies * Chronic immunosuppressant or antiinflammatory use * Dialysis through temporary catheter or single puncture

Locations (2)

Hospital Clinic de Barcelona

Barcelona, Barcelona, Spain

CSU Bellvitge

L'Hospitalet de Llobregat, Barcelona, Spain

Outcomes

Primary Outcomes

Survival

Time frame: 36 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.