Clinical Evaluation of the Effect of Duodenal-Jejunal Bypass on Type 2 Diabetes

Inclusion Criteria: * Adults age 20-65 years * Clinical diagnosis of type II diabetes buy on of the following three criteria (American Diabetes Association) 1. A normal or high C-peptide level (to exclude type 1 diabetes) (\>.9ng/ml) 2. A random plasma glucose of 200mg/dl or more with typical symptom of diabetes 3. A fasting plasma glucose of 126mg/dl or more on more than one occasion * BMI 22-34 KG/m2 * Patients on oral hypoglycemic medications or insulin to control T2DM * Inadequate control of diabetes as defined as HbA1c\>7.5 * No contraindication for surgery or General Anesthesia as determined by multidisciplinary surgical team * Ability to understand and describe the mechanism of action of ricks and benefits of the operation Exclusion Criteria: * Patients who meet any of the following exclusion criteria will be exclusion criteria will be excluded from enrollment into the study * Enrolled in another clinical study which involves and investigational drug * Diagnosis type 1 diabetes * Pregnancy (all female patients will have beta HCG) or planned pregnancy within 2 years of entry into the study or unwilling to use reliable contraceptive method * Previous gastric or esophageal surgery * Immunosuppressive drugs including corticosteroids * Coagulopathy (INR\>1.5 or platelets\<50,000/ul) * Anemia (Hgb\<10.0g/dl)