Excimer Lamp Versus Excimer Laser in Vitiligo Treatment

Centre Hospitalier Universitaire de Nice

Overview

308 nm excimer lamp and 308 nm excimer laser have both provide interesting results in treating vitiligo. They have the same wavelength but the type of emission of the photons is different. To date there is no direct comparative data concerning these two devices in this indication. The aim of the study is to make an intra-individual prospective comparison between these two phototherapies.

Study Type

INTERVENTIONAL

Conditions

Vitiligo

Interventions

308nm excimer lampRADIATION

50 mJ/cm² below the MED (minimal erythemal dose) and progressive increase Twice a week for 12 weeks

308nm excimer laserRADIATION

50 mJ/cm² below the MED (minimal erythemal dose) and progressive increase Twice a week for 12 weeks (same doses will be used between the 2 arms)

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patient above 18 * vitiligo for more than 3 months * at least 2 vitiligo symmetric patches more than 10cm² * to read and understand the inform consent * to have a social security number * non pregnant for women Exclusion Criteria: * pregnant women * keloids * history of radiotherapy or skin cancer in the treated areas * treatment for vitiligo in the past 4 weeks * phototherapy in the past 12 weeks; history of photodermatosis * treatment inducing photosensibilization * immunosuppression * patient who participated in a study in the past 3 months

Locations (1)

Department of Dermatology, University Hospital of Nice

Nice, France

Outcomes

Primary Outcomes

Repigmentation rate in the treated areas

Time frame: 12 weeks

Secondary Outcomes

Tolerance and safety of the treatments

Time frame: 12 weeks

Data from ClinicalTrials.gov

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